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A Droplet Based Multi-Drug Screening System Controlled With Electrostatic Microvalves

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dc.contributor.author Yıldırım, Ender
dc.contributor.author Özgür, E.
dc.contributor.author Kulah, Haluk
dc.date.accessioned 2020-04-28T19:56:42Z
dc.date.available 2020-04-28T19:56:42Z
dc.date.issued 2012
dc.identifier.citation Yıldırım, Ender; Özgür, E.; Külah, H.; "A Droplet Based Multi-Drug Screening System Controlled With Electrostatic Microvalves", Proceedings of the 16th International Conference On Miniaturized Systems for Chemistry and Life Sciences, Microtas 2012, pp. 959-961, (2012). tr_TR
dc.identifier.isbn 978-097980645-2
dc.identifier.uri http://hdl.handle.net/20.500.12416/3469
dc.description.abstract This paper presents a droplet-based drug effect analysis system utilizing electrostatically-actuated normallyclosed microvalves to screen the effect of multiple drugs on a single type of cell. Proposed system minimizes the need for off-chip equipment by utilizing parylene based electrostatic microvalves. Prototypes of the system were fabricated and tested using colored DI water and 3 μm diameter micro beads, emulating drugs and cells respectively. During the tests, micro beads could be successfully entrapped in 137 pl droplets. Tests carried out with yeast cells also yielded successful encapsulation of the cells. It was shown that, switching between the drugs could be achieved by applying 200 V dc to operate the microvalves. tr_TR
dc.language.iso eng tr_TR
dc.publisher Chemical and Biological Microsystems Society tr_TR
dc.rights info:eu-repo/semantics/closedAccess tr_TR
dc.subject Electrostatic tr_TR
dc.subject Microvalve tr_TR
dc.subject Multi-drug Screening tr_TR
dc.subject Parylene tr_TR
dc.title A Droplet Based Multi-Drug Screening System Controlled With Electrostatic Microvalves tr_TR
dc.type bookPart tr_TR
dc.relation.journal Proceedings of the 16th International Conference On Miniaturized Systems for Chemistry and Life Sciences, Microtas 2012 tr_TR
dc.contributor.authorID 31835 tr_TR
dc.identifier.startpage 959 tr_TR
dc.identifier.endpage 961 tr_TR
dc.contributor.department Çankaya Üniversitesi, Mühendislik Fakültesi, Makine Mühendisliği Bölümü tr_TR


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