DSpace Repository

Silicon-based core-shell nanoparticle's nanobiomedical characterisation

Show simple item record

dc.contributor.author Sana, Farzin Asghari
dc.contributor.author Farhadnia, Farshad
dc.contributor.author Salmanogli, Ahmad
dc.date.accessioned 2024-05-14T07:52:38Z
dc.date.available 2024-05-14T07:52:38Z
dc.date.issued 2019
dc.identifier.citation Sana, Farzin Asghari; Farhadnia, Farshad; Salmanogli, Ahmad. (2019). "Silicon-based core-shell nanoparticle's nanobiomedical characterisation", International Journal of Nanoparticles, Vol.11, No.4, pp.283-293. tr_TR
dc.identifier.issn 17532507
dc.identifier.uri http://hdl.handle.net/20.500.12416/8257
dc.description.abstract Using functionalised nanoparticles in nanobiomedical applications cause to raise questions about unintentional effect of such powerful agents on the human body. In other words, the study of nanoparticle toxicity can be considered as a curtail key for the biological applications. In this study, the core/shell nanoparticles such as Si/Au and SiO2/Au were synthesised and functionalised with some biological elements. For satisfying some medical standards and biomedical critical test conditions, a few in-vitro assays as cytotoxicity and haemolysis should be done. For this reason, cytotoxicity and haemolytic effects of the functionalised nanoparticles such as Si/Au/biotin and SiO2/Au/biotin and their derivatives were evaluated on Hep-G2 cells and humane red blood samples. It is shown that cytotoxicity and haemolysis effects of the all synthesised nanoparticles are concentration-dependent. Also, the results are shown that most cytotoxicity and haemolytic effects are observed for Si/Au and SiO2/Au without biotin groups after 48 hours and 30 minutes, respectively. tr_TR
dc.language.iso eng tr_TR
dc.relation.isversionof 10.1504/IJNP.2019.104258 tr_TR
dc.rights info:eu-repo/semantics/closedAccess tr_TR
dc.subject Haemolysis tr_TR
dc.subject MTT Cytotoxicity Assay tr_TR
dc.subject Nanocytotoxicity tr_TR
dc.subject Silicon Core/Shell Nanoparticle tr_TR
dc.title Silicon-based core-shell nanoparticle's nanobiomedical characterisation tr_TR
dc.type article tr_TR
dc.relation.journal International Journal of Nanoparticles tr_TR
dc.identifier.volume 11 tr_TR
dc.identifier.issue 4 tr_TR
dc.identifier.startpage 283 tr_TR
dc.identifier.endpage 293 tr_TR
dc.contributor.department Çankaya Üniversitesi, Mühendislik Fakültesi, Elektrik-Elektronik Mühendisliği Bölümü tr_TR


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record