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An experimental investigation of flow resistance and turbulent flow in brush fish pass

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dc.contributor.author Küçükali, Serhat
dc.date.accessioned 2020-01-31T11:54:21Z
dc.date.available 2020-01-31T11:54:21Z
dc.date.issued 2019-10
dc.identifier.citation Kucukali, Serhat, "An experimental investigation of flow resistance and turbulent flow in brush fish pass", Proceedings of the Institution of Civil Engineers-Water Management, Vol. 172, No. 5, pp. 241-256, (2019). tr_TR
dc.identifier.issn 1741-7589
dc.identifier.uri http://hdl.handle.net/20.500.12416/2400
dc.description.abstract The present study aimed to search for chicken abdominal fat deposition-related polymorphisms within RB1 and to provide functional evidence for significantly associated genetic variants. Association analyses showed that 11 single nucleotide polymorphisms (SNPs) in intron 17 of RB1, were significantly associated with both abdominal fat weight (P < 0.05) and abdominal fat percentage (P < 0.05). Functional analysis revealed that the A allele of g.32828A>G repressed the transcriptional efficiency of RB1 in vitro, through binding nuclear factor-kappa B (NF-B-K) and SRY-related HMG box protein 2 (SOX2). Furthermore, RB1 mRNA expression levels in the abdominal fat tissue of individuals with the A/A genotype of g.32828A>G were lower than those of individuals with the G/G genotype. Collectively, we propose that the intronic SNP g.32828A>G of RB1 is an obesity-associated variant that directly affects binding with NF-B-K and SOX2, leading to changes in RB1 expression which in turn may influence chicken abdominal fat deposition. tr_TR
dc.language.iso eng tr_TR
dc.publisher Ice Publishing tr_TR
dc.relation.isversionof 10.1680/jwama.18.00019 tr_TR
dc.rights info:eu-repo/semantics/closedAccess tr_TR
dc.subject Hydraulics & Hydrodynamics tr_TR
dc.subject Models (Physical) tr_TR
dc.subject River Engineering tr_TR
dc.title An experimental investigation of flow resistance and turbulent flow in brush fish pass tr_TR
dc.type article tr_TR
dc.relation.journal Proceedings of the Institution of Civil Engineers-Water Management tr_TR
dc.contributor.authorID 20413 tr_TR
dc.identifier.volume 172 tr_TR
dc.identifier.issue 5 tr_TR
dc.identifier.startpage 241 tr_TR
dc.identifier.endpage 256 tr_TR
dc.contributor.department Çankaya Üniversitesi, Mühendislik Fakültesi, İnşaat Mühendisliği Bölümü tr_TR


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