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Comparative study of the continuous wavelet transform, derivative and partial least squares methods applied to the overlapping spectra for the simultaneous quantitative resolution of ascorbic acid and acetylsalicylic acid in effervescent tablets

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dc.contributor.author Dinç, Erdal
dc.contributor.author Özdemir, Abdil
dc.contributor.author Baleanu, Dumitru
dc.date.accessioned 2020-04-16T21:07:04Z
dc.date.available 2020-04-16T21:07:04Z
dc.date.issued 2005-03-09
dc.identifier.citation Dinç, E.; Özdemir, A.; Baleaunu, D., "Comparative study of the continuous wavelet transform, derivative and partial least squares methods applied to the overlapping spectra for the simultaneous quantitative resolution of ascorbic acid and acetylsalicylic acid in effervescent tablets", Journal Of Pharmaceutical And Biomedical Analysis , Vol.37, No.3, pp.569-575, (2005). tr_TR
dc.identifier.issn 0731-7085
dc.identifier.uri http://hdl.handle.net/20.500.12416/3237
dc.description.abstract The simultaneous spectrophotometric determination of ascorbic acid (AA) and acetylsalicylic acid (ASA) in effervescent tablets in the presence of the overlapping spectra was accomplished by the continuous wavelet transform (CWT), derivative spectrophotometry (DS) and partial least squares (PLS) approaches without using any chemical pre-treatment. CWT and DS calibration equations for AA and ASA were obtained by measuring the CWT and DS amplitudes corresponding to zero-crossing points of spectra obtained by plotting continuous wavelet coefficients and first-derivative absorbance values versus the wavelengths, respectively. The PLS calibration was constructed by using the concentration set and its full absorbance data consisting of 850 points from 220 to 305 urn in the range of 210-310 nun. These three methods were tested by analyzing the synthetic mixtures of the above drugs and they were applied to the real samples containing two commercial pharmaceutical preparations of subjected drugs. A comparative study was carried out by using the experimental results obtained from three analytical methodologies and precise and accurate results were obtained. tr_TR
dc.language.iso eng tr_TR
dc.publisher Elsevier Science BV tr_TR
dc.relation.isversionof 10.1016/j.jpba.2004.11.020 tr_TR
dc.rights info:eu-repo/semantics/closedAccess tr_TR
dc.subject Continuous Wavelet Transform tr_TR
dc.subject Derivative Spectrophotometry tr_TR
dc.subject Partial Least Squares tr_TR
dc.subject Ascorbic Acid tr_TR
dc.subject Acetylsalicylic Acid tr_TR
dc.subject Effervescent Tablets tr_TR
dc.title Comparative study of the continuous wavelet transform, derivative and partial least squares methods applied to the overlapping spectra for the simultaneous quantitative resolution of ascorbic acid and acetylsalicylic acid in effervescent tablets tr_TR
dc.type article tr_TR
dc.relation.journal Journal Of Pharmaceutical And Biomedical Analysis tr_TR
dc.contributor.authorID 56389 tr_TR
dc.identifier.volume 37 tr_TR
dc.identifier.issue 3 tr_TR
dc.identifier.startpage 569 tr_TR
dc.identifier.endpage 575 tr_TR
dc.contributor.department Çankaya Üniversitesi, Fen Edebiyat Fakültesi, Matematik Bölümü tr_TR


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